Stage five is kidney failure which is also referred to as “End Stage Renal Disease.” Your glomerular filtration rate will be less than 15. This means your kidneys are no longer eliminating enough waste that your body produces from your blood. This is called uremia. You may feel ill. Some people experience nausea and vomiting, anorexia (no appetite), edema (swelling of limbs), fatigue and weakness. Other diseases that you have may be exacerbated by the stage of kidney disease. At this stage it is time to execute the predetermined plan of action that you and your nephrologist may have decided upon in stage four.